Biology Research Associate I - Center for Protein Degradation

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Job ID:

450 Brookline Ave, Boston, MA 02215

Research Laboratory

Employment Type:
Full time

Work Location:
Onsite: Full time on Campus


Dana-Farber Cancer Institute (DFCI) and Deerfield Management have created the Center for Protein Degradation (CPD) at DFCI. The CPD has created a next-generation protein degrader and molecular glue platform to advance novel therapeutic modalities. This is an exceptional opportunity to join a newly founded research center that is pushing the boundaries of targeted protein degradation research and accelerating the translation of basic science into clinical solutions.  Join our highly interactive team of scientists where we are creating new avenues of therapeutic intervention.

Our Culture

CPD believes...

  • learning is paramount, failure is necessary to succeed, and humility is an asset.
  • every individual should have the opportunity to provide and solicit feedback; asking for help is a strength.
  • in helping others succeed – we celebrate our successes together and recognize the contributions of the team.
  • in scientific excellence, challenging dogma, and asking “WHY?”
  • our research must push scientific boundaries and accelerate the discovery of transformational medicines.

 CPD is seeking a biology research associate to join our team. The individual will work as part of a multidisciplinary team to identify and characterize novel molecular glues and degraders. They will be centrally involved in various drug discovery projects, primarily in developing and running biological assays, as well as target validation. In addition to the bench-based research, responsibilities will also include some aspects of laboratory management and organization. Training is available in all aspects of experimental research.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


  • Conduct cellular and ex vivo experiments, including standard biological and laboratory analyses and assays
  • Maintain cell lines and prepare laboratory reagents
  • Compile and analyze experimental data. Develop a summary of findings for presentation to Center personnel
  • Use computer-interfaced equipment, robotics, and high-technology applications to perform work duties
  • Maintain clean and organized work areas and order supplies, as needed
  • Set up, calibrate, and operate lab equipment
  • Keep up to date with appropriate literature related to work and projects
  • May be responsible for designing and executing advanced experiments
  • Maintain clear and accurate records of experimental work (e.g., experiment methods, results/findings) in a lab notebook
  • Monitor laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory

Research Associate I – No supervisory responsibilities. 


  • Bachelor's or Master’s Degree in biology or biochemistry
  • Knowledge of western blotting, ELISA, qPCR, and cell culture with 1-2 years of professional experience preferred
  • Excellent communication skills (written and verbal)
  • Ability to document and analyze information/data and use logic to address work-related issues and problems
  • Organized with close attention to detail and strong time management skills. Thorough in completing work tasks
  • A strong team player who also demonstrates an ability to work independently as required

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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