Research Technician - Chronic Lymphocytic Leukemia

Job Details

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Job ID:
31143

Location:
450 Brookline Ave, Boston, MA 02215

Category:
Research Laboratory

Employment Type:
Full time

Work Location:
Onsite:Up to 1 day remote/wk

Overview

The Dana-Farber Cancer Institute seeks an experienced and motivated research technician to assist with studies of the molecular mechanisms leading to the development of Chronic Lymphocytic leukemia (CLL), the most common adult leukemia of mature B lymphocytes.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Responsibilities

This position will be working on projects in the CLL Center led by Dr. Jennifer Brown but will be working closely with Dr. Paolo Ghia’s group for training and techniques.  

The CLL center is known for its fundamental contributions to the development of innovative therapies for CLL, specifically designed to tackle key pathogenetic mechanisms of the disease, at the crossroads between immunology and hematology. The successful applicant will join a vibrant research team investigating the different phases of the natural history of CLL, in particular focusing on the B cell antigen receptors (immunoglobulins) and related signaling pathways, and their role in the evolution of the disease from the initial stages to relapsed refractory disease. To this aim, the Unit intends to identify pathways and molecules relevant to leukemia progression and that can potentially be used as diagnostic markers, prognostic factors or new potential therapeutic targets.

Research methodology is based on the integration of experimental results obtained from the study of normal and neoplastic B lymphocytes, using cell culture, multicolor flow cytometry and molecular biology techniques including PCR and sequencing. Computer expertise and skills in database management of scientific data will be a plus.

  • Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
  • Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
  • Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.
  • Isolate, identify and prepare specimens for examination.
  • Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff. 
  • Participate in grant application process and manuscript preparation as required.
  • Maintains detailed notebook of all work-related activities.
  • Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
  • Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
  • May be responsible for the development, modification and improvement of standard operating procedures.
  • Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
  • May be responsible for designing and executing advanced experiments and setting strategy. 
  • May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
  • May be responsible for monitoring laboratory budgets.

Qualifications

The ideal candidate should be highly motivated, enthusiastic, and capable of working in a team as well as independently and possess excellent organizational and communication skills. Previous experience will be privileged.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

  • Bachelor's Degree required with a major in biology or chemistry preferred. 
  • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
  • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
  • Ability to analyze information and use logic to address work-related issues and problems.
  • Must have attention to detail and be thorough in completing work tasks.
  • Ability to work within a team environment.


Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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