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Job ID:

450 Brookline Ave, Boston, MA 02215

Research Technician/Scientist

Employment Type:
Full time

Work Location:
Onsite:Up to 1 day remote/wk


The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology Lab that combines molecular biology, computational biology, structural biology and chemistry with various ‘Omics’ techniques to study the pathways and protein complexes involved in the regulation of protein homeostasis often associated with human diseases, including cancer. Using our knowledge of the cellular degradation machinery, we use structure and computational guided approaches to develop new molecules that hijack the ubiquitin proteasome system for targeted protein degradation.

The Fischer Lab ( seeks a highly motivated individual to join the team as a Lab Manager. This individual would work closely with, and support, the PI in managing the running of the overall lab including the day-to-day operations. This includes; responsibility for ensuring the lab and group are well organized and have all that is needed to function, equipment planning and maintenance, space allocation, training of lab members on core principles and procedures. In addition, the individual would work closely with the PI and senior lab staff to provide support for projects, collaborations and partnering with industry. A key function would be the continuous development of the lab as a state-of-the-art environment for cutting edge science, which involves long-term planning of equipment needs related to on-boarding of new technologies, as well as laboratory space considerations.

This is an excellent opportunity to work in a vibrant environment and at the cutting edge of basic science and drug discovery both within the lab and the Dana-Farber Cancer Institute as well as through collaboration with external laboratories and industry.


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


  • Manage and organize lab operations, which includes but is not limited to:
    • Enable daily lab operations. Ensure that all lab staff have all that is needed to run projects.
    • Coordinate equipment maintenance and repair.
    • Lab procurement. Work with purchasing and DFCI staff to ensure procurement and purchasing of all lab reagents/equipment. Maintain lab ordering system and work with lab staff.
    • Space planning and assignment.
    • Equipment planning and procurement.
    • Keeps track of general lab practices and protocols and works with senior staff to resolve issues and implement improvements.
    • Manages the onboarding, training and offboarding of employees in the group.
  • Support the preparation of reporting: To funding agencies, foundations, institutions.
  • Support PI in day to day needs (work with existing administrative support for PI to streamline processes).


  • Bachelors, MS, PhD, or MD in biomedical sciences, engineering or related field.
  • Excellent written and oral communication skills (English).
  • 3+ year experience in a lab technician, lab operations or lab management role. Experience in a similar role in industry or academia will be considered.
  • Excellent decision-making, communication, and collaboration skills with proven cross-functional and multi-level relationship building skills.
  • Attention to detail, a practical mindset and ability to multi-task.
  • Ability to lead/influence others.
  • Experience with maintaining lab equipment (e.g. automated FPLC and HPLC systems, standard wet lab equipment, multimode plate readers).
  • Experience with automation/robotics is highly desired.
  • Experience in directly working with support functions in larger organizations (e.g. finance, purchasing, HSE, or building services) is desired.
  • Background in research related to the general interests (drug discovery, biochemistry, drugging the ubiquitin system) of the lab is a plus.
  • Experience in procurement is a plus.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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