Postdoctoral Research Fellow - Mittendorf Lab

Job Details

Job ID:

450 Brookline Ave, Boston, MA 02215


Employment Type:
Full time

Work Location:
Onsite: 100% onsite


Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Dana-Farber Cancer Institute is looking for an enthusiastic postdoctoral fellow with an interest in cancer biology and tumor immunology to work on our existing and upcoming projects to address the impact of age and race on the immune response to cancer and cancer therapies under the supervision of Sandra McAllister, PhD and Elizabeth Mittendorf, MD, PhD.

Our group studies breast tumor immunology focusing on an individual patient’s peripheral immune system and  immune aspects of the tumor microenvironment that impact the development of breast cancer and response to standard therapies. We utilize novel multiplex imaging modalities to allow single cell spatial resolution, routine and single cell transcriptomic analyses, flow cytometry, and routine immunologic assays as well as complex in vitro models among other techniques. By more fully characterizing the peripheral immune system as well as immune aspects of the breast tumor microenvironment we aim to identify factors predictive of developing breast cancer as well as to biomarkers of response to therapy including immunotherapy.  Our collaborative program utilizes biospecimens from patients receiving standard therapy as well as experimental therapies in the setting of clinical trials which are analyzed using state of the art technologies in the research laboratory. Our findings are subsequently validated in in vitro and in vivo models in order to inform subsequent translation to the clinic to improve the care of breast cancer patients.



Characteristic duties:

  • Technical proficiency, scientific creativity, collaboration with others and independent thought.
  • Work independently on scientific projects identified by the post-doctoral fellow in consultation with Drs. McAllister and Mittendorf.
  • Work collaboratively with other postdoctoral fellows, research assistants and technicians in the group.
  • Proficiency with immunologic methods and preclinical animal models.
  • Analysis of data from experiments to include multi-omic analyses.
  • Maintain detailed and understandable lab notebooks.
  • Interpret and discuss research findings with lab members and the principal investigator.
  • Develop figures to depict research findings, write research and review papers, and present at scientific meetings.


At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


Accomplished and motivated candidates will have an MD or PhD degree. A background in immunology is preferred. Existing skills in standard immunologic assays, flow cytometry, tissue culture, and preclinical animal models are desirable. Clear thinking, writing, and communication skills are absolutely needed. A record of scientific accomplishment as shown by a peer-reviewed original research paper(s) is desirable. 

EEOC Poster

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