The Gelb Laboratory at Dana-Farber Cancer Institute and Harvard Medical School studies Genitourinary Oncologic (GU) cancers, particularly prostate, kidney and other genitourinary cancers. We utilize variety of molecular biology and genomic approaches to understand GU cancer with major focus areas including: 1) Defining and validating the essential factors in GU cancers involved in response to immunotherapy; 2) Understanding the genetic and phenotypic changes that drive cancer progression through genomic and transcriptomic analysis of tumor biopsies; 3) Functional studies on mechanisms involved in resistance to targeted drug therapies. Research in the laboratory ranges from basic mechanistic investigation of cancer gene function to highly translational genomic and functional studies of patient-derived tissues from clinical trials. Team members work in a highly collaborative environment that includes laboratory investigators, clinical investigators and computational biologists at Dana-Farber Cancer Institute. We are seeking enthusiastic, dedicated and hardworking post-doctoral scientists to join our team. The successful candidate will have a strong interest in cancer biology and therapeutics with experience in molecular biology, cell biology, genetics/genomics or biochemistry.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
A post-doc. position is available in the Gelb Center for Translational Research under the supervision of Dr. Toni Choueiri. The Gelb Center leverages our biobank of patient samples to answer important questions focused on different aspects of kidney, bladder, and prostate cancers. We are specifically interested in molecular genetic programs that are involved in cancer progression and cancer response to specific targeted therapies or immunotherapy. Frequently used techniques include mammalian cell culture, transcriptomics, and functional assays.
Specific responsibilities may include: