Research Operations Manager I

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Job ID:

450 Brookline Ave, Boston, MA 02215


Employment Type:
Full time

Work Location:
Onsite:Up to 1 day remote/wk


Th DFCI Center for Immuno-Oncology (CIO) is a multi-disciplinary group dedicated to the discovery, development, and first-in-human clinical trials of novel immunotherapies. The Center for Immuno-Oncology established the Immune Assessment Laboratory to assist investigators at Dana-Farber Cancer Institute, its partners and external sites in establishing mechanistic and biomarker endpoints for clinical studies. With the recent success of immunotherapies through vaccines and checkpoint blockade targeted monoclonal antibodies, the goal of our Laboratory is to provide researchers with access to the latest innovations in immune monitoring in a quality-controlled setting.

The Lab offers technical support and scientific advice to investigators at Dana-Farber Cancer Institute and its partners who are interested in performing clinical studies related to cancer immunotherapies.  We provide data generation for clinical trials across multiple disease centers as well as the necessary expertise to design and develop assays related to cancer immunology biomarkers.  We are also involved in the collection of blood and solid tissue from patients participating in more than 50 clinical trials at DFCI as well as multiple external sites. Our Lab is equipped with the latest technologies for the detection of soluble biomarkers, next generation sequencing, as well as determining cellular phenotypes.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

This position is responsible for facilitating a faculty member's research program through management of the laboratory operations. Responsibility will include assistance with PI's administrative responsibilities in the laboratory; supervision of technical staff to manage and maintain good laboratory practice. This individual will report directly to the PI and work closely with PI's executive administrator and Research Science Manager and Department Administrator.


      • Institute, maintain, and improve standard procedures for laboratory efficiencies
      • Responsible for overseeing efficient inventory maintenance and ordering
      • Responsible, directly or indirectly, for care, repair and maintenance of laboratory equipment
      • Ensure good laboratory practice through training and guidance of technicians and trainees
      • Arrange core seminars for research staff with vendors for equipment trainings
      • Responsible for managing efficient and effective administration of laboratory protocols and research materials/stocks
      • Responsible for distribution and cataloguing of laboratory notebooks
      • Assist lab supervisors with, teaching, training, mentoring, orientation, in-service and continuing education for laboratory staff and trainees.
      • Ensures all lab staff are compliant with DFCI and sponsor mandatory trainings.
      • Perform protein detection techniques such as ELISAs Luminex, Mass cytometry and flow cytometry


  • Bachelor degree in Biology or healthcare related science, with experience in an immunology, oncology, biomedical or pathology laboratory setting
  • Experience in management of medium size research laboratory (>10 FTEs) in the field of biological sciences, with 1-3 years of research management is required.
  • Familiarity with cancer research laboratory operations including equipment maintenance, safety, compliance and record keeping
  • Exceptional people management and organization skills, with demonstrated ability to multi-task to enable many concurrent projects in a complex, fast paced environment. 
  • Excellent quantitative, analytic, and problem solving skills to evaluate all aspects of a problem opportunity and make or facilitate appropriate and timely decisions. 
  • Excellent interpersonal skills, including the ability and willingness to work closely with other colleagues as a team; experience and comfort in working with individuals with diverse backgrounds and differing viewpoints; openness to new ideas. 
  • Proficiency in Word, Excel, PowerPoint.
  • Flow cytometry expertise and data analysis with FlowJo
  • Experience in cell culture techniques including culture, maintenance and storage of mammalian cell lines
  • ELISAs type assays experience (preferred)
  • Experience with human immune cell banking and biospecimen storage systems preferred
    Keep regular, detailed and accurate documentation of lab activities

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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