Job ID:
38491

Location:
450 Brookline Ave, Boston, MA 02215

Category:
Research Laboratory

Employment Type:
Full time

Work Location:
Onsite: 100% onsite

Overview

Dr. Himisha Beltran is a translational researcher and medical oncologist at the Dana-Farber Cancer Institute (DFCI) and Associate Professor of Medicine at Harvard Medical School (HMS). She is seeking a highly motivated, exceptional clinical research technician to assist in both lab-based and clinical research. Dr. Beltran’s lab has developed therapeutic targets and biomarkers for prostate cancer. They have led the molecular characterization of patient tumors and preclinical studies to understand mechanisms underlying resistance.  In addition, they have developed genomic and epigenetic assays for clinical trials. Further information on the Beltran Lab can be found by visiting their website:

Beltran Lab - Precision Medicine and Prostate Cancer Research - HOME (dana-farber.org)

The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity.  In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.   

This individual will support the research team in the overall conduct of clinical and translational research using Good Clinical Practice under the auspices of the Principal Investigator Dr. Beltran. The candidate will be responsible for the primary data collection and management of patient clinical information as it pertains to translational research studies. S/he will ensure timely collection of related samples as required, and may be responsible for IRB protocol submissions. This individual may also screen patients for translational research eligibility, obtain informed consent, and register study participants to clinical trials. The successful candidate will also conduct experiments involving human cancer biospecimens, process blood and tissue samples, perform immunohistochemistry, extract DNA and RNA, and prepare libraries for next-generation sequencing.  The individual will also assist in daily laboratory operations and organization. In addition, s/he will collaborate with a diverse array of community members at DFCI and HMS, including molecular biologists, medical oncologists, pathologists, epidemiologists, genomics specialists, and computational scientists. There is potential for contributions to be published and presented in several forums.

Located in Boston and the surrounding communities, DFCI is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other HMS-affiliated hospitals.

Responsibilities

  • Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
  • Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
  • Conduct standardized biological, microbiological or biochemical tests and laboratory analyses, including the collection of information and samples from organic substances, such as blood, drugs, and animals.
  • Isolate, identify and prepare specimens for examination.
  • Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff. 
  • Participate in grant application process and manuscript preparation as required.
  • Maintains detailed notebook of all work-related activities.
  • Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
  • Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
  • May be responsible for the development, modification and improvement of standard operating procedures.
  • Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
  • May be responsible for designing and executing advanced experiments and setting strategy. 
  • May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
  • May be responsible for monitoring laboratory budgets.
  • Extract clinical data and research data from electronic medical records and other sources and enters this data in the clinical paper-based or electronic data capture system for each assigned study.
  • Develop and maintain database(s) with clinical data and tissue annotation
  • Manages a workload of studies commensurate to level of experience.
  • Answers data clarifications (i.e., data queries) for each study.
  • Schedules and meets with study monitors and assures patient cases are ready for each monitor visit and items are addressed after each monitoring visit.
  • Develops source data worksheets specific to each assigned study.
  • Assures clinical issues from monitoring reports are addressed and closed out before the next monitoring visit.
  • Assures all study requirements are documented and meet both internal and external regulations in accordance with protocol guidelines.
  • Maintains logs in a timely manner according to department SOPs.
  • Participates in site initiation visits (SIV), monitoring visits and participates in site disease group (SDG) team and PI oversight meetings as required.
  • Assists multidisciplinary team in research activities.
  • Maintains study binders and filings according to protocol requirements and department policy.
  • Adheres to all department policies and procedures.
  • Compiles patient data for Investigator review to determine patient eligibility for protocol enrollment.
  • Maintains screening, enrollment, adverse event, deviation, tumor measurement, concomitant medication, delegation and other sponsor and/or protocol specific logs.
  • Ensures work environment is organized and functions efficiently. Participates in a collaborative, empowered work environment as demonstrated through teamwork. Demonstrates a level of professional practice that supports the delivery of appropriate care and positive working relationships throughout the medical center.
  • Adheres to University and unit-level policies and procedures and safeguards University assets.
  • Prepare and or complete regulatory related reports and IRB submissions.
  • Maintain and organize study regulatory binders, enter all required study data on an ongoing basis.
  • Interact with study participants as directed/required by the protocol and/or study team.
  • Blood processing and tissue sample work including processing blood and tissue samples, performing immunohistochemistry, extracting DNA and RNA, preparing libraries for next-generation sequencing. 
  • Assist in daily laboratory operations and organization.

Qualifications

  • Bachelor's Degree required with a major in biology or chemistry preferred. 
  • At least 1-2 years of related experience working in a medical or scientific research setting. More experienced applicants who have worked for multiple years as a professional scientist or research technician are also encouraged to apply and would be considered at an appropriate level of compensation and benefits.

KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:

  • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
  • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
  • Ability to analyze information and use logic to address work-related issues and problems.
  • Must have attention to detail and be thorough in completing work tasks.
  • Ability to work within a team environment.
  • Must practice discretion and adhere to hospital confidentiality guidelines at all times. 
  • Must have computer skills including the use of Microsoft Office.
  • A strong scientific curiosity and a “can-do” attitude is required to be successful for this position

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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