Research Technician-Shih Lab

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450 Brookline Ave, Boston, MA 02215

Research Technician/Scientist

Employment Type:
Full time


The Dana-Farber Cancer Institute is seeking a highly motivated and capable individual for a Research Technician position in the laboratory of Dr. William Shih at the Dana-Farber Cancer Institute in Boston, MA. The Shih Laboratory explores design principles for self-assembling molecular machines. As our model system, we primarily use structural DNA nanotechnology. We seek to apply our knowledge towards construction of artificial systems that help solve problems of biological and medical interest. Currently we focus on building tools for molecular biophysics (e.g. macromolecular structure determination and single-molecule assays) and tools for diagnostics and therapeutics (e.g. nanoparticle adjuvants for vaccines).

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


The responsibilities for the Research Technician will be to assist postdoctoral fellows and graduate students in conducting experiments on programmable self-assembly of DNA nanostructures. A major responsibility will involve production and purification of DNA strands needed for the self-assembly experiments. Another major responsibility will be characterization of DNA nanostructures using agarose-gel electrophoresis and negative-stain transmission electron microscopy. More generally, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.


Bachelor's Degree required with a major in the natural sciences or engineering preferred. Knowledge of information and techniques related to molecular biology is preferred. Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff. Must have attention to detail and be thorough in completing work tasks. The candidate should be open-minded, creative, energetic, and critical thinking.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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