Research Technician - Translational Immunogenomics Lab

Job Details

Job ID:

450 Brookline Ave, Boston, MA 02215

Research Laboratory

Employment Type:
Full time

Work Location:
Onsite: 100% onsite


The Dana Farber Cancer Institute (DFCI) brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Translational Immunogenomics Lab (TIGL) within DFCI uses state-of-the-art genomic technologies to assess the response of the immune system to cancer and therapy. TIGL evaluates the latest developments in the field, implements the optimal methods for the task at hand, and invents methods when current approaches are inadequate. The current focus of TIGL is discovering patient-specific neoantigens, understanding the details and consequences of interactions between neoantigens and T cells, and applying this knowledge to support neoantigen immunization therapy.

The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity.  In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.   

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


A full-time position is available for a highly motivated research technician to join the Translational Immunogenomics Lab (TIGL) team. Work tasks will include:

  • Preparing and sequencing libraries from single-cell and bulk RNA
  • Preparing and sequencing libraries that combine analysis of DNA, RNA, and/or protein
  • Performing single-cell qPCR assays for RNA expression, genotyping, and splicing variants
  • Generating plasmid constructs for mammalian expression
  • Preparing reagents and media used in lab experiments
  • Operating and maintaining lab equipment

Training is available in all procedures; some experience in the above techniques is preferred.

We are looking for candidates who have at least two years of availability. The job will provide great exposure to someone who is considering going to graduate school or medical school in the future.



Research Technician

No supervisory responsibilities.  Normally receives detailed instructions on all work.



  • Minimum of B.A./B.S. with experience in molecular biology. Major in biology or chemistry is preferred.
  • Some previous laboratory experience is required.


  • Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
  • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
  • Ability to analyze information and use logic to address work-related issues and problems.
  • Must have attention to detail, meticulous record-keeping skills, and be thorough in completing work tasks.
  • Ability to work within a team environment.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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