Senior Research Technician - Filbin Lab

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Job ID:

450 Brookline Ave, Boston, MA 02215

Research Laboratory

Employment Type:
Full time

Work Location:
Onsite:Up to 1 day remote/wk


A multi-disciplinary team of researchers led by Dr. Mariella G. Filbin at the Dana-Farber Cancer Institute and Boston Children’s Hospital (with co-affiliation with the Broad Institute of MIT and Harvard) seeks a Senior Research Technician/Lab manager to join efforts to find new treatment strategies for pediatric brain tumors. Our team uses cutting-edge single cell genomics as well as gene editing tools to understand the hierarchies of cancer cells within tumors and their interaction with the microenvironment, with a particular focus on cancer stem-cell programs and their translation into novel treatments.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


  • Conduct standardized biological, molecular and biochemical tests and laboratory analyses, including the collection and processing of samples directly from patients.
  • Conduct both single-cell and bulk RNA and DNA sequencing experiments from primary patient tumors.
  • Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May participate in formal and information presentations of results to staff. 
  • Participate in grant application process and manuscript preparation as required.
  • Maintains detailed notebook of all work-related activities.
  • Monitor laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to the laboratory.
  • Responsible for the development, modification, and improvement of standard operating procedures.
  • Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
  • Clean, maintain and prepare supplies and work areas.
  • Organize and record the location of biological samples and supplies.
  • Responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
  • May be responsible for monitoring laboratory budgets.
  • Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
  • Use computers, computer-interfaced equipment, robotics, or high-technology applications to perform work duties.
  • May be responsible for designing and executing advanced experiments and setting strategy. 


At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

  • Bachelor's Degree required with a major in molecular biology, biochemistry, genetics/genomics or neuroscience preferred.
  • Minimum of 3-5 years related experience. Knowledge of information and techniques related to either molecular biology, genomics, chemistry, or medicine is preferred.
  • Must have excellent communication skills (written and verbal) and be excited to work with a wide variety of faculty and staff.
  • Ability to analyze information and use logic to address work-related issues and problems.
  • Must have attention to detail and be thorough in completing work tasks.
  • Ability to thrive in a multi-disciplinary team environment.
  • Passion for scientific discovery to improve patient outcomes and highly self-motivated.

A minimum two-year commitment is required. Start date flexible (ideally early 2022).

Please contact Mariella G. Filbin at if interested. We are committed not only to conducting rigorous research to find better treatments for children with brain tumors, but also to providing an open platform to train future scientists, regardless of your background. In addition to your resume/CV, please answer the questions below (~100 words) that are designed for us to get to know you better and your reasons for applying for this position.

  1. What are some experiences, either in a research or non-research setting, that illustrate your independence, leadership, and ability to work in a team?
  2. What motivates you to pursue research?
  3. Why are you specifically interested in working in the Filbin Lab and what do you hope to learn from this research opportunity?
  4. Briefly describe a failure or challenge you have experienced and how you approached it.
  5. Is there anything else you would like us to know? (optional)

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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