Senior Research Technician

Job Details

Job ID:

450 Brookline Ave, Boston, MA 02215

Research Laboratory

Employment Type:
Full time

Work Location:
Onsite: 4-5 days onsite/week


We are seeking to hire a highly motivated senior research technician with enthusiasm in wet-lab science, who will support and lead cancer genomic research projects. The successful candidate will join the team of Dr. Bradley Bernstein, will work primarily with postdoctoral researchers and will assist with general lab management when needed . This role also includes collaboration opportunities with partner laboratories in the Boston area.

The technician will be trained by the lab manager postdocs and senior technicians. They will work closely with peers in the laboratory as a supportive member and in turn will receive training and career mentoring from Dr. Bernstein and senior lab members. There will be the opportunity to attend scientific retreats and conferences, present papers at Journal Club and present your work at weekly lab meetings amongst others.

A two-year commitment is strongly preferred.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physicians/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


  • Designs, executes and analyses standard experimental procedures as assigned (i.e. – pipetting, cell and tissue culture, PCR, etc.)
  • Executes and troubleshoots genomic assays and gene editing protocols, including, single-cell RNA-seq, CRISPR-Cas9 editing and other specialized protocols.
  • Performs drug treatments and biochemical pharmacologic assays.
  • Maintains lab reagents, chemicals and sample database.
  • Sets up and prepares routine experiments as directed.
  • Conducts analysis and interpretation of observed results for preparation of reports and project summaries.
  • Performs appropriate literature reviews in order to contribute intellectually to assigned projects.
  • May be responsible for operation and maintenance of standard lab equipment.
  • Multiple scientific duties are currently available including a role with part-time responsibilities to monitor mouse colony – sets up breeding pairs, genotypes progeny, executes experiments with supervision, maintains colony database. Previous training in mouse handling is preferred but not required.


  • Bachelor's degree required.
  • Technically meticulous when conducting experiments.
  • Highly organized in record-keeping.
  • Strong communication and interpersonal skills.
  • 1+ years of prior research experience in related area (beyond a classroom setting).
  • Prior experience in mouse work is a plus.
  • Prior experience programming in R or Python or interest in learning basic programming is a plus.
  • Ability to work independently and as a team member.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring and inclusive environment where every patient, family and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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