The Eck lab uses structural, biochemical and biophysical approaches to study protein kinase regulation and other aspects of cellular signal transduction. We use our structural and mechanistic insights to drive development of novel anti-cancer drugs. Systems of current interest in the lab include RAF-family kinases and their control of the …
A joint computational chemistry postdoctoral position is available in Eck lab and Computational Chemistry Core for a motivated individual to develop and apply cutting-edge computational techniques to guide the design and optimization of small molecule modulators for RAS/RAF pathway, activated mutant EGFR, and other cancer drug targets. The Eck lab …
