Overview
A full-time position is available for a highly motivated research technician to contribute to investigating mechanisms of immune escape in cancer, and in particular to the study of the role and regulation of nonclassical HLA class I molecules in lymphoma models. The laboratory uses a variety of techniques in molecular biology, immunology, genome-wide CRISPR screening, peptidomics, and single cell technologies to better understand how HLAs are regulated, define their antigen repertoire, and how their interaction with the immune system shapes the tumor microenvironment and response to immune-based therapies. The technician will be responsible for basic cloning and molecular biology approaches, lentiviral generation for CRISPR technologies, generation of CAR-T cells, in vivo mouse modeling, molecular and cellular immunology workflows including flow cytometry and spatial proteomics. The technician should have excellent record keeping skills, and a drive to learn new technologies. Training is available in all protocols and procedures; experience with basic technique in molecular biology is strongly preferred.
We are seeking candidates with a minimum of two years of availability.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities
The candidate will be expected to independently carry out essential research functions in the laboratory that include but are not limited to experience in cell and molecular biology techniques.
Specifically, the candidate is expected to:
SUPERVISORY RESPONSIBILITIES:
Research Technician
No supervisory responsibilities. Normally receives detailed instructions on all work.
Qualifications
The ideal candidate should possess strong communication and organizational skills, attention to detail, and the ability to perform in a team environment. An interest in pursuing advanced education in MD, PhD, or MD-PhD programs in the future is preferred.
The position requires:
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.