Lab Manager - Cancelas Lab

Job Details

Job ID:

450 Brookline Ave, Boston, MA 02215

Research Laboratory

Employment Type:
Full time

Work Location:
Onsite: 100% onsite


This position is responsible for facilitating a senior faculty member’s research program through management of the laboratory operations and specifically the management of mice colonies. Responsibility will include assistance with PI’s administrative responsibilities in the laboratory and supervision of technical staff to manage and maintain good laboratory practice.  This individual will report directly to the PI and work closely with PI’s executive administrator, Research Science Manager and Department Administrator.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


Laboratory Operations

  • Institute, maintain, and improve standard procedures for laboratory efficiencies, including monitoring laboratory expenditure.
  • Responsible for efficient management of mouse colonies through proper allocation of technical support resources as need in response to scientific need, and support the PI in the generation of new or amended animal protocols for IACUC review.
  • Responsible for overseeing efficient inventory maintenance and ordering. This includes flow antibodies, restriction enzymes, proteins, plasmids, and DNA to name a few.
  • Responsible, directly or indirectly, for care, repair and maintenance of laboratory equipments.
  • Ensure good laboratory practice directly or indirectly through supervised activities of technicians and trainees.


Scientific Operations

  • Assist PI in monitoring, enabling and facilitate collaborations with other programs.
  • Active intellectual involvement in research projects is encouraged.
  • Ability to manage mice colonies, genotype multi-transgenic animals and conduct breeding of multiple strains.
  • Ability to conduct western blot, PCR, flow cytometry, and tissue culture.
  • Ability to generate and titer defective gamma-retroviral and lentiviral supernatants, including testing for RCR/RCL particles as requested the Institutional Biosafety Committee.



  • Highly organized, able to use efficiently databases and maintain curated records.
  • Responsible for managing efficient and effective administration of laboratory protocols and research materials/stocks.
  • Train and manage staff scientists and research technicians and guide recruitment of technical staff.
  • Responsible for annual reviews of technical staff performance.
  • Assist PI with counseling, teaching, training, mentoring, orientation, in-service and continuing education for laboratory staff and trainees.
  • Ensures all lab staff are compliant with DFCI, NIH and sponsor mandatory trainings.



  • Bachelor’s Degree in a scientific discipline required; Master’s degree preferred
  • Experience in managing mouse colonies is required
  • A minimum of 3-5 years of experience in management of research laboratory in the field of biological sciences
  • Strong knowledge of HR activities and solid writing skills preferred
  • Familiarity with cancer research laboratory operations including equipment maintenance, safety, compliance and record keeping


  • Exceptional people management and organization skills, with demonstrated ability to multi-task to enable many concurrent projects in a complex, fast paced environment.
  • Excellent quantitative, analytic, and problem solving skills to evaluate all aspects of a problem opportunity and make or facilitate appropriate and timely decisions.
  • Excellent interpersonal skills, including the ability and willingness to work closely with other colleagues as a team; experience and comfort in working with individuals with diverse backgrounds and differing viewpoints; openness to new ideas.
  • Proficiency in Microsoft Office Word, Excel, Access, PowerPoint.


Oversees needs of a laboratory composed initially by 4 members, with growth expectations to up to 16 members.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

Interested individuals should apply on line and contact: Jose A. Cancelas MD, PhD (Principal Investigator). E-mail:

EEOC Poster

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