Sr. Research Technician - CAR T Cell Pre-clinical

Job Details

Job ID:

450 Brookline Ave, Boston, MA 02215

Research Laboratory

Employment Type:
Full time

Work Location:
Onsite: 100% onsite


Sr. Research Technician - CAR T cell Pre-clinical 

Pre-clinical lab developing next generation cellular immunotherapies focused on CAR T cell immunotherapy for cancer is looking for an exceptionally motivated individual with past lab experience to join the lab team of Dr. Eric Smith, Director of Translational Research, Immune Effector Cell Therapies at Dana Farber. The lab takes projects from conception to transgene design /genetic engineering, through reduction to practice, in vitro and in vivo studies, and ultimately translation to the clinic. The position involves mammalian cell culture, flow cytometry, molecular biology (plasmid construction, CRISPR gene editing), viral transduction to generate gene modified immune effector cells.

Dr. Smith is deeply committed to the growth and success of each trainee that joins the lab. He believes that mentorship is not something that happens in the background as trainees pursue their research, but should be intentional, thought out, and personalized for each member of the group. He spends the time to meet trainees' individual needs, not only in terms of their scientific growth, but also with a focus on career goals and development.

The Dana Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic.  The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must. Normally receives detailed instructions on all work.

The research technician will assist scientists in performing scientific research and development of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.

This full-time position will also include some general lab duties as outlined below.

This position will start Summer 2024 or earlier.


    • Basic biochemical, molecular, and cell biology skills as the applicant’s contribution is expected to contribute significantly toward developing research projects.
    • Opportunities to design and perform experiments both individually and collaboratively, and address problems in experimental protocols.
    • Analyze experimental data and interpret results to write reports and summaries of findings.  Expected to participate in formal and informal presentations of results.
    • Participate in grant application process and manuscript preparation as required.
    • Maintains detailed electronic notebook of all work-related activities.
    • Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
    • Responsible for the development, modification and improvement of standard operating procedures.
    • Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
    • Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies.
    • May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
    • Intellectual input and co-authorship are encouraged.


    Research Technician

    No supervisory responsibilities. 

    Normally receives general instructions on routine work, detailed instructions on new projects or assignments.


    • Bachelor’s Degree required with a major in biology or chemistry preferred.   Typically requires a minimum of 1-4 years related experience.  Developing technical expertise, applies Institute policies and procedures to resolve a variety of issues.  Works on problems of moderate scope where analysis of situations or data requires a review of a variety of factors.  Exercises judgment within defined procedures and practices to determine appropriate action.  Builds productive internal/external working relationships


    • Learns and uses technical principles, processes, and concepts.
    • Applies Institute policies and procedures to resolve routine issues.
    • Works on problems of limited scope.
    • Follows standard practices and procedures in analyzing situations or data from which answers can be readily obtained.
    • Builds stable working relationships internally
    • Exceptionally self-motivated
    • Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
    • Outstanding planning, organizational, multi-tasking skills
    • Ability to analyze information and use logic to address work-related issues and problems.
    • Must have attention to detail and be thorough in completing work tasks.
    • Ability to work within a team environment.

    At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

    Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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