Overview
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Our efforts are focused on understanding the basic biology of HNSCCs and translating these findings to benefit patients. These are divided into below approaches.
1. HNSCC modeling
a. Developed syngeneic HNSCC cell lines called the mouse oral carcinoma (MOC) model.
b. Generated a bank of patient derived xenografts oral cavity SCCAs
c. Current efforts include expanding PDX modeling and generating antiPD1 resistant, syngeneic models
2. Neoantigen biology and immunotherapy response
3. Immunotherapy resistance including with CRISPR screening
4. Mechanisms of response and resistance to MEK inhibition in HNSCCs
5. Clinical trials- novel neoadjuvant clinical trial approaches. PI or co-investigator in below trials
The goal of our laboratory efforts is to couple understanding of the basic biology of head and neck squamous cell carcinomas (HNSCCs) with translational findings to ultimately transform how we take care of affected patients.
We study the basic immunobiology of the anti-tumor immune response, pathways impacted by targeted therapeutics and correlative clinical responses in HNSCC patients.
We utilize (1) preclinical HNSCC model systems, (2) patient derived samples and xenografts and (3) novel clinical trial designs that together advance our understanding of HNSCCs.
Primary Duties and Responsibilities
Knowledge, Skills and Abilities
Minimum Job Qualifications
License/Certification/Registration Required: None
Supervisory Responsibilities:
Patient Contact: None
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$95,000.00 - $125,100.00